Analysis of advanced sterilization technology in cosmetic bottle container

In the field of sterilization and disinfection of cosmetic packaging bottles in China's cosmetics industry for many years, there are defects due to the use of the old technology. Referring to the international advanced disinfection industry, the ozone disinfection system of "jzcf-b" series packaging containers is designed and manufactured in accordance with the requirements of "GMP validation guide" and "disinfection technical specifications" formulated by the Ministry of health, with obvious disinfection effect. The packaging container of cosmetics needs advanced sterilization process analysis;



1、 Principle of ozone sterilization


Ozone sterilization belongs to biochemical oxidation reaction. Ozonation decomposes the enzymes necessary for the internal oxidation of glucose by bacteria; it can also directly interact with bacteria and viruses, destroy their cell walls and RNA, decompose DNA, RNA, protein, lipids and polysaccharides and other macromolecular polymers, so as to destroy the material metabolism, growth and reproduction of bacteria; it can also penetrate the membrane tissue and invade the membrane and act on the outer membrane lipids The protein and lipopolysaccharide inside the cell cause the cell to have the permeability distortion, which causes the cell to dissolve and die. The genetic gene, parasitic strain, parasitic virus particle, phage, mycoplasma and pyrogen (bacterial virus metabolite, endotoxin) in the body of the dead bacteria are dissolved and die out. Generally speaking, the principle of aseptic technology can be divided into bacteriostasis, sterilization and bacteriolysis. Ozone is a bacteriolytic agent.


In the technical code for disinfection issued by the Ministry of health in 1991, there is also an introduction to the sterilization principle of ozone:


"Scientific research shows that ozone has a very strong bactericidal effect." "Under normal temperature and pressure, the molecular structure of ozone is unstable, and it can decompose into oxygen (O2) and single oxygen atom (o) by itself. The latter has strong activity and has strong oxidation effect on bacteria. Ozone oxidation breaks down the enzymes necessary for glucose oxidation in bacteria, thus destroying the cell membrane and killing it. The extra oxygen atoms will be self-assembled into ordinary oxygen molecules (O2), without any toxic residues, so it is called "pollution-free disinfectant". It can not only kill all kinds of bacteria (including hepatitis virus, e



2、 Working principle and system composition


Through the sterilization and disinfection practice of different packaging containers with ozone, the corresponding effective ozone disinfection concentration is calculated to obtain the effective concentration time period, and then the data is set in the centralized electronic control system for storage, and the whole disinfection process can be automatically controlled in production. Through the effective concentration of ozone, the packaging materials are sterilized and sterilized thoroughly in a specified period of time until the exhaust gas is discharged to the atmosphere after being destroyed (the exhaust gas meets the ozone concentration ≤ 0.2mg/m3 of the national environmental protection standard).


The system is composed of air source treatment equipment, ozone generation equipment, ozone concentration monitoring and detection equipment, tail gas emission destruction equipment and centralized electrical automatic control.


The air source treatment equipment supplies the treated gas to the ozone generation equipment to generate ozone, which diffuses to the inner cavity of the packaging material through the pipeline in the disinfection bin. When the ozone concentration and action time in the disinfection bin reach the specified value, the ozone generation equipment stops working, and the tail gas destruction equipment starts preheating. When the temperature reaches the set value, the tail gas discharge equipment starts, and the gas in the bin is discharged and sent When the tail gas destroys the equipment, it is forced to decompose and reduce rapidly and discharge into the atmosphere.


System process: air source treatment - ozone generator - disinfection Bin - exhaust gas emission damage